PFKFB3 is a bifunctional enzyme that modulates and maintains the intracellular concentrations of fructose-2,6-bisphosphate (F2,6-P2), essentially controlling the rate of glycolysis.PFKFB3 is a known activator of glycolytic rewiring in neoplastic cells, including central nervous system (CNS) neoplastic cells.The pathologic regulation of PFKFB3 is in
Chemometric Assessment of Soil Pollution and Pollution Source Apportionment for an Industrially Impacted Region around a Non-Ferrous Metal Smelter in Bulgaria
The present study deals with the assessment of pollution caused by a large industrial facility using multivariate statistical methods.The primary goal Utility Pouches is to classify specific pollution sources and to apportion their involvement in the formation of the total concentration of the chemical parameters being monitored.This aim is accompl
Clinical audit in dentistry: From a concept to an initiation
Clinical audit is a quality improvement process that aims to improve patient care through a systematic POS review of care against explicit criteria.It is a cyclic and multidisciplinary process which involves a series of steps from planning the audit through measuring the performance to implementing and sustaining the change.Although audit contains
Treatment of COVID-19: Perspective on Convalescent Plasma Transfusion
The novel coronavirus (COVID-19) has continued its global spread since the first documented case in late 2019 in Wuhan, China.With DVDs over 10 million cases and 500 thousand deaths reported worldwide, the need for an effective treatment regimen is evident.Historically, convalescent plasma (CP) has been utilized in the treatment of viral respirator